|
Symbol Name ID |
Ttn
titin MGI:98864 |
| * | Aspects of the system are reported to show a normal phenotype. |
| Darker colors indicate more annotations |
| Human Phenotypes | Cardiomyopathy |
Dilated cardiomyopathy |
Hypertrophic cardiomyopathy |
Reduced left ventricular ejection fraction |
Severely reduced left ventricular ejection fraction |
Arrhythmia |
Sudden cardiac death |
Atrial fibrillation |
Premature atrial contractions |
Atrioventricular reentrant tachycardia |
Ventricular tachycardia |
Atrioventricular block |
Congestive heart failure |
| Disease(s) Associated with TTN | |||||||||||||
| autosomal recessive limb-girdle muscular dystrophy type 2J | |||||||||||||
| congenital myopathy 5 | |||||||||||||
| dilated cardiomyopathy 1G | |||||||||||||
| hypertrophic cardiomyopathy 9 | |||||||||||||
| tibial muscular dystrophy |
| Mouse Phenotypes | cardiovascular system phenotype |
abnormal cardiovascular system morphology |
abnormal blood vessel morphology |
abnormal dorsal aorta morphology |
abnormal angiogenesis |
absent organized vascular network |
abnormal myocardium layer morphology |
abnormal myocardial fiber morphology |
increased myocardial fiber size |
abnormal myocardial trabeculae morphology |
trabecula carnea hypoplasia |
thin myocardium |
heart left ventricle hypertrophy |
abnormal cardiovascular development |
abnormal heart development |
abnormal heart morphology |
increased heart left atrium weight |
abnormal heart left atrium morphology |
decreased heart weight |
cardiac hypertrophy |
ventricular hypoplasia |
abnormal heart ventricle morphology |
abnormal heart left ventricle morphology |
increased heart left ventricle weight |
increased heart left ventricle size |
dilated heart left ventricle |
thick ventricular wall |
pericardial edema |
pericardial effusion |
cardiac interstitial fibrosis |
dilated cardiomyopathy |
abnormal blood circulation |
decreased diastolic filling velocity |
hemorrhage |
abnormal cardiac muscle contractility |
decreased cardiac muscle contractility |
decreased ventricle muscle contractility |
increased left ventricle diastolic pressure |
increased left ventricle systolic pressure |
absent heartbeat |
abnormal myocardial fiber physiology |
|
| Availability | Mouse Genotype | |||||||||||||||||||||||||||||||||||||||||
| Ttnem1Kage/Ttnem1Kage | * | |||||||||||||||||||||||||||||||||||||||||
| Ttnshru/Ttnshru | ||||||||||||||||||||||||||||||||||||||||||
| Ttntm1.1Her/Ttntm1.1Her | ||||||||||||||||||||||||||||||||||||||||||
| Ttntm1.1Hgra/Ttntm1.1Hgra | ||||||||||||||||||||||||||||||||||||||||||
| Ttntm1.1Isrd/Ttntm1.1Isrd | ||||||||||||||||||||||||||||||||||||||||||
| Ttntm1Brge/Ttntm1Brge | ||||||||||||||||||||||||||||||||||||||||||
| Ttntm1Mgot/Ttntm1Mgot | ||||||||||||||||||||||||||||||||||||||||||
| Ttntm2.1Hgra/Ttntm2.1Hgra | ||||||||||||||||||||||||||||||||||||||||||
| Ttntm2.1Mgot/Ttntm2.1Mgot | ||||||||||||||||||||||||||||||||||||||||||
| Ttntm1Brge/Ttn+ | * | |||||||||||||||||||||||||||||||||||||||||
| Ttntm1Her/Ttntm1Her Tg(Ckmm-cre)5Khn/0 (conditional) |
* | |||||||||||||||||||||||||||||||||||||||||
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
||
|
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support. |
last database update 04/30/2024 MGI 6.23 |
|
|
|
||
Analysis Tools